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Dental follicle mesenchymal stem cell administration ameliorates muscle weakness in MuSK-immunized mice

BACKGROUND: Myasthenia gravis (MG) is an antibody-mediated autoimmune disease of the neuromuscular junction (NMJ), mostly associated with acetylcholine receptor (AChR) antibodies. Around 5–10 % of MG patients show antibodies to muscle-specific tyrosine kinase (MuSK). Mesenchymal stem cell (MSC) admi...

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Detalles Bibliográficos
Autores principales: Ulusoy, Canan, Zibandeh, Noushin, Yıldırım, Selin, Trakas, Nikolaos, Zisimopoulou, Paraskevi, Küçükerden, Melike, Tașlı, Hatice, Tzartos, Socrates, Göker, Kamil, Tüzün, Erdem, Akkoç, Tunç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673854/
https://www.ncbi.nlm.nih.gov/pubmed/26646841
http://dx.doi.org/10.1186/s12974-015-0451-0