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Mechanisms downstream of reverse transcription reduce serum levels of HBV DNA but not of HBsAg in chronic hepatitis B virus infection

BACKGROUND: Hepatitis B virus (HBV) DNA in serum of chronically infected patients declines by 3–4 log(10) units at loss of HBe antigen (HBeAg) from serum. The mechanisms behind this decline, and the much smaller decline of surface antigen (HBsAg) levels, are still not well known. The aim of this stu...

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Detalles Bibliográficos
Autores principales: Larsson, Simon B., Malmström, Sebastian, Hannoun, Charles, Norkrans, Gunnar, Lindh, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673857/
https://www.ncbi.nlm.nih.gov/pubmed/26645241
http://dx.doi.org/10.1186/s12985-015-0447-5