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Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection
Biochemical reactions are subject to stochastic fluctuations that can give rise to cell-to-cell variability. Yet, how this variability affects viral infections, which themselves involve noisy reactions, remains largely elusive. Here we present single-cell experiments and stochastic simulations that...
Autores principales: | Heldt, Frank S., Kupke, Sascha Y., Dorl, Sebastian, Reichl, Udo, Frensing, Timo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673863/ https://www.ncbi.nlm.nih.gov/pubmed/26586423 http://dx.doi.org/10.1038/ncomms9938 |
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