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Exercise training restores the cardiac microRNA-1 and −214 levels regulating Ca(2+) handling after myocardial infarction

BACKGROUND: Impaired cardiomyocyte contractility and calcium handling are hallmarks of left ventricular contractile dysfunction. Exercise training has been used as a remarkable strategy in the treatment of heart disease. The microRNA-1, which targets sodium/calcium exchanger 1 (NCX), and microRNA-21...

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Detalles Bibliográficos
Autores principales: Melo, Stéphano Freitas Soares, Barauna, Valério Garrone, Neves, Vander José, Fernandes, Tiago, Lara, Lucienne da Silva, Mazzotti, Diego Robles, Oliveira, Edilamar Menezes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673865/
https://www.ncbi.nlm.nih.gov/pubmed/26646371
http://dx.doi.org/10.1186/s12872-015-0156-4