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Structure and substrate selectivity of the 750-kDa α(6)β(6) holoenzyme of geranyl-CoA carboxylase

Geranyl-CoA carboxylase (GCC) is essential for the growth of Pseudomonas organisms with geranic acid as the sole carbon source. GCC has the same domain organization and shares strong sequence conservation with the related biotin-dependent carboxylases 3-methylcrotonyl-CoA carboxylase (MCC) and propi...

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Detalles Bibliográficos
Autores principales: Jurado, Ashley R., Huang, Christine S., Zhang, Xing, Zhou, Z. Hong, Tong, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673880/
https://www.ncbi.nlm.nih.gov/pubmed/26593090
http://dx.doi.org/10.1038/ncomms9986