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Open access chemical probes for epigenetic targets

BACKGROUND: High attrition rates in drug discovery call for new approaches to improve target validation. Academia is filling gaps, but often lacks the experience and resources of the pharmaceutical industry resulting in poorly characterized tool compounds. DISCUSSION: The SGC has established an open...

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Detalles Bibliográficos
Autores principales: Brown, Peter J, Müller, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673908/
https://www.ncbi.nlm.nih.gov/pubmed/26397018
http://dx.doi.org/10.4155/fmc.15.127