Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem-like cells and identifies additional targets for radiosensitization

Toward developing a model system for investigating the role of the microenvironment in the radioresistance of glioblastoma (GBM), human glioblastoma stem-like cells (GSCs) were grown in coculture with human astrocytes. Using a trans-well assay, survival analyses showed that astrocytes significantly...

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Detalles Bibliográficos
Autores principales: Rath, Barbara H, Wahba, Amy, Camphausen, Kevin, Tofilon, Philip J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673998/
https://www.ncbi.nlm.nih.gov/pubmed/26518290
http://dx.doi.org/10.1002/cam4.510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673998/
https://www.ncbi.nlm.nih.gov/pubmed/26518290
http://dx.doi.org/10.1002/cam4.510

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