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An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils
For the treatment of monogenetic hematological disorders, restoration of transgene expression in affected cell populations is generally considered to have beneficial effects. However, X-linked chronic granulomatous disease (XCGD) is unique since the appearance of functional neutrophils in the periph...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674005/ https://www.ncbi.nlm.nih.gov/pubmed/26682238 http://dx.doi.org/10.1038/mtm.2015.46 |