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An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils

For the treatment of monogenetic hematological disorders, restoration of transgene expression in affected cell populations is generally considered to have beneficial effects. However, X-linked chronic granulomatous disease (XCGD) is unique since the appearance of functional neutrophils in the periph...

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Detalles Bibliográficos
Autores principales: Lin, Huan-Ting, Masaki, Hideki, Yamaguchi, Tomoyuki, Wada, Taizo, Yachie, Akihiro, Nishimura, Ken, Ohtaka, Manami, Nakanishi, Mahito, Nakauchi, Hiromitsu, Otsu, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674005/
https://www.ncbi.nlm.nih.gov/pubmed/26682238
http://dx.doi.org/10.1038/mtm.2015.46