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Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier

Mitochondrial ADP/ATP carriers catalyze the equimolar exchange of ADP and ATP across the mitochondrial inner membrane. Structurally, they consist of three homologous domains with a single substrate binding site. They alternate between a cytoplasmic and matrix state in which the binding site is acces...

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Detalles Bibliográficos
Autores principales: King, Martin S., Kerr, Matthew, Crichton, Paul G., Springett, Roger, Kunji, Edmund R.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674015/
https://www.ncbi.nlm.nih.gov/pubmed/26453935
http://dx.doi.org/10.1016/j.bbabio.2015.09.013