Hes1 Increases the Invasion Ability of Colorectal Cancer Cells via the STAT3-MMP14 Pathway

The Notch pathway contributes to self-renewal of tumor-initiating cell and inhibition of normal colonic epithelial cell differentiation. Deregulated expression of Notch1 and Jagged1 is observed in colorectal cancer. Hairy/enhancer of split (HES) family, the most characterized targets of Notch, invol...

Descripción completa

Detalles Bibliográficos
Autores principales: Weng, MT, Tsao, PN, Lin, HL, Tung, CC, Change, MC, Chang, YT, Wong, JM, Wei, SC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674118/
https://www.ncbi.nlm.nih.gov/pubmed/26650241
http://dx.doi.org/10.1371/journal.pone.0144322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674118/
https://www.ncbi.nlm.nih.gov/pubmed/26650241
http://dx.doi.org/10.1371/journal.pone.0144322

Ejemplares similares