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Hes1 Increases the Invasion Ability of Colorectal Cancer Cells via the STAT3-MMP14 Pathway

The Notch pathway contributes to self-renewal of tumor-initiating cell and inhibition of normal colonic epithelial cell differentiation. Deregulated expression of Notch1 and Jagged1 is observed in colorectal cancer. Hairy/enhancer of split (HES) family, the most characterized targets of Notch, invol...

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Detalles Bibliográficos
Autores principales:	Weng, MT, Tsao, PN, Lin, HL, Tung, CC, Change, MC, Chang, YT, Wong, JM, Wei, SC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674118/ https://www.ncbi.nlm.nih.gov/pubmed/26650241 http://dx.doi.org/10.1371/journal.pone.0144322

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