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Cooperation between CD4+ T Cells and Humoral Immunity Is Critical for Protection against Dengue Using a DNA Vaccine Based on the NS1 Antigen

Dengue virus (DENV) is spread through most tropical and subtropical areas of the world and represents a serious public health problem. At present, the control of dengue disease is mainly hampered by the absence of antivirals or a vaccine, which results in an estimated half worldwide population at ri...

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Detalles Bibliográficos
Autores principales: Gonçalves, Antônio J. S., Oliveira, Edson R. A., Costa, Simone M., Paes, Marciano V., Silva, Juliana F. A., Azevedo, Adriana S., Mantuano-Barradas, Marcio, Nogueira, Ana Cristina M. A., Almeida, Cecília J., Alves, Ada M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674122/
https://www.ncbi.nlm.nih.gov/pubmed/26650916
http://dx.doi.org/10.1371/journal.pntd.0004277