Presence of Rheumatoid Factor during Chronic HCV Infection Is Associated with Expansion of Mature Activated Memory B-Cells that Are Hypo-Responsive to B-Cell Receptor Stimulation and Persist during the Early Stage of IFN Free Therapy

Approximately half of those with chronic hepatitis C virus (HCV) infection have circulating rheumatoid factor (RF), and a portion of these individuals develop cryoglobulinemic vasculitis. B cell phenotype/function in relation to RF in serum has been unclear. We examined B cell subset distribution, a...

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Detalles Bibliográficos
Autores principales: Reyes-Avilés, Elane, Kostadinova, Lenche, Rusterholtz, Anne, Cruz-Lebrón, Angelica, Falck-Ytter, Yngve, Anthony, Donald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674123/
https://www.ncbi.nlm.nih.gov/pubmed/26649443
http://dx.doi.org/10.1371/journal.pone.0144629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674123/
https://www.ncbi.nlm.nih.gov/pubmed/26649443
http://dx.doi.org/10.1371/journal.pone.0144629

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