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HSP90 Inhibitor Geldanamycin as a Radiation Response Modificator in Human Blood Cells
Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone, involved in the folding, assembly, stabilization and activation of numerous proteins with unrelated amino acid sequences and functions. Geldanamycin (GA), a natural benzoquinone, can inhibit the chaperone activity of Hsp90. It...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674165/ https://www.ncbi.nlm.nih.gov/pubmed/26674599 http://dx.doi.org/10.2203/dose-response.14-039.Stankova |