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HSP90 Inhibitor Geldanamycin as a Radiation Response Modificator in Human Blood Cells

Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone, involved in the folding, assembly, stabilization and activation of numerous proteins with unrelated amino acid sequences and functions. Geldanamycin (GA), a natural benzoquinone, can inhibit the chaperone activity of Hsp90. It...

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Detalles Bibliográficos
Autores principales:	Stankova, Katia, Savova, Gergana, Nikolov, Vladimir, Boteva, Rayna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674165/ https://www.ncbi.nlm.nih.gov/pubmed/26674599 http://dx.doi.org/10.2203/dose-response.14-039.Stankova

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