A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

Keratin intermediate filaments (KIFs) protect the epidermis against mechanical force, support strong adhesion, help barrier formation, and regulate growth. The mechanisms by which type I and II keratins contribute to these functions remain incompletely understood. Here, we report that mice lacking a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Vinod, Bouameur, Jamal-Eddine, Bär, Janina, Rice, Robert H., Hornig-Do, Hue-Tran, Roop, Dennis R., Schwarz, Nicole, Brodesser, Susanne, Thiering, Sören, Leube, Rudolf E., Wiesner, Rudolf J., Vijayaraj, Preethi, Brazel, Christina B., Heller, Sandra, Binder, Hans, Löffler-Wirth, Henry, Seibel, Peter, Magin, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674273/
https://www.ncbi.nlm.nih.gov/pubmed/26644517
http://dx.doi.org/10.1083/jcb.201404147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674273/
https://www.ncbi.nlm.nih.gov/pubmed/26644517
http://dx.doi.org/10.1083/jcb.201404147

Ejemplares similares