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EGFR Regulates the Development and Microarchitecture of Intratumoral Angiogenic Vasculature Capable of Sustaining Cancer Cell Intravasation

Many malignant characteristics of cancer cells are regulated through pathways induced by the tyrosine kinase activity of the epidermal growth factor receptor (EGFR). Herein, we show that besides directly affecting the biology of cancer cells per se, EGFR also regulates the primary tumor microenviron...

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Detalles Bibliográficos
Autores principales: Minder, Petra, Zajac, Ewa, Quigley, James P., Deryugina, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674488/
https://www.ncbi.nlm.nih.gov/pubmed/26408256
http://dx.doi.org/10.1016/j.neo.2015.08.002