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EGFR Regulates the Development and Microarchitecture of Intratumoral Angiogenic Vasculature Capable of Sustaining Cancer Cell Intravasation
Many malignant characteristics of cancer cells are regulated through pathways induced by the tyrosine kinase activity of the epidermal growth factor receptor (EGFR). Herein, we show that besides directly affecting the biology of cancer cells per se, EGFR also regulates the primary tumor microenviron...
Autores principales: | Minder, Petra, Zajac, Ewa, Quigley, James P., Deryugina, Elena I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674488/ https://www.ncbi.nlm.nih.gov/pubmed/26408256 http://dx.doi.org/10.1016/j.neo.2015.08.002 |
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