Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

Genome-wide association studies have been tremendously successful in identifying genetic variants associated with complex diseases. The majority of association signals are intergenic and evidence is accumulating that a high proportion of signals lie in enhancer regions. We use Capture Hi-C to invest...

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Detalles Bibliográficos
Autores principales: Martin, Paul, McGovern, Amanda, Orozco, Gisela, Duffus, Kate, Yarwood, Annie, Schoenfelder, Stefan, Cooper, Nicholas J., Barton, Anne, Wallace, Chris, Fraser, Peter, Worthington, Jane, Eyre, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674669/
https://www.ncbi.nlm.nih.gov/pubmed/26616563
http://dx.doi.org/10.1038/ncomms10069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674669/
https://www.ncbi.nlm.nih.gov/pubmed/26616563
http://dx.doi.org/10.1038/ncomms10069

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