A tunable artificial circadian clock in clock-defective mice

Self-sustaining oscillations are essential for diverse physiological functions such as the cell cycle, insulin secretion and circadian rhythms. Synthetic oscillators using biochemical feedback circuits have been generated in cell culture. These synthetic systems provide important insight into design...

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Detalles Bibliográficos
Autores principales: D'Alessandro, Matthew, Beesley, Stephen, Kim, Jae Kyoung, Chen, Rongmin, Abich, Estela, Cheng, Wayne, Yi, Paul, Takahashi, Joseph S., Lee, Choogon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674671/
https://www.ncbi.nlm.nih.gov/pubmed/26617050
http://dx.doi.org/10.1038/ncomms9587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674671/
https://www.ncbi.nlm.nih.gov/pubmed/26617050
http://dx.doi.org/10.1038/ncomms9587

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