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Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress
Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserved enzyme in the NAD synthetic pathway. It has also been identified as an effective and versatile neuroprotective factor. However, it remains unclear how healthy neurons regulate the dual functions of NMNAT and achieve self-protecti...
Autores principales: | Ruan, Kai, Zhu, Yi, Li, Chong, Brazill, Jennifer M., Zhai, R. Grace |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674693/ https://www.ncbi.nlm.nih.gov/pubmed/26616331 http://dx.doi.org/10.1038/ncomms10057 |
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