Cargando…

Polymorphisms of BCL2 and BAX Genes Associate with Outcomes in Advanced Non-small cell lung cancer Patients treated with platinum-based Chemotherapy

Single-nucleotide polymorphisms (SNP) of the gene belonging to the BCL2 family are thought to play a role in chemotherapy resistance. This study investigated the association of BCL2-938C>A(rs2279115) and BAX-248G>A(rs4645878) promoter region SNPs and the clinical responses and outcomes of 235...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Yu, Wang, Linang, Qing, Yi, Li, Chongyi, Ren, Tao, Li, Qing, Li, Mengxia, Zhang, Shiheng, Shan, Jinglu, Wang, Ge, Yang, Zhenzhou, Wang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674711/
https://www.ncbi.nlm.nih.gov/pubmed/26656462
http://dx.doi.org/10.1038/srep17766