Cargando…

Identification of Novel Inhibitors of Organic Anion Transporting Polypeptides 1B1 and 1B3 (OATP1B1 and OATP1B3) Using a Consensus Vote of Six Classification Models

[Image: see text] Organic anion transporting polypeptides 1B1 and 1B3 are transporters selectively expressed on the basolateral membrane of the hepatocyte. Several studies reveal that they are involved in drug–drug interactions, cancer, and hyperbilirubinemia. In this study, we developed a set of cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Kotsampasakou, Eleni, Brenner, Stefan, Jäger, Walter, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674819/
https://www.ncbi.nlm.nih.gov/pubmed/26469880
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00583