SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling

AMP-activated protein kinase (AMPK) inhibits several anabolic pathways such as fatty acid and protein synthesis, and identification of AMPK substrate specificity would be useful to understand its role in particular cellular processes and develop strategies to modulate AMPK activity in a substrate-sp...

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Detalles Bibliográficos
Autores principales: Yan, Yan, Ollila, Saara, Wong, Iris P. L., Vallenius, Tea, Palvimo, Jorma J., Vaahtomeri, Kari, Mäkelä, Tomi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674823/
https://www.ncbi.nlm.nih.gov/pubmed/26616021
http://dx.doi.org/10.1038/ncomms9979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674823/
https://www.ncbi.nlm.nih.gov/pubmed/26616021
http://dx.doi.org/10.1038/ncomms9979

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