Functional redundancy of transcription factors explains why most binding targets of a transcription factor are not affected when the transcription factor is knocked out

BACKGROUND: Biologists are puzzled by the extremely low percentage (3%) of the binding targets of a yeast transcription factor (TF) affected when the TF is knocked out, a phenomenon observed by comparing the TF binding dataset and TF knockout effect dataset. RESULTS: This study gives a plausible bio...

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Detalles Bibliográficos
Autores principales: Wu, Wei-Sheng, Lai, Fu-Jou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674858/
https://www.ncbi.nlm.nih.gov/pubmed/26678747
http://dx.doi.org/10.1186/1752-0509-9-S6-S2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674858/
https://www.ncbi.nlm.nih.gov/pubmed/26678747
http://dx.doi.org/10.1186/1752-0509-9-S6-S2

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