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A model for gene deregulation detection using expression data

In tumoral cells, gene regulation mechanisms are severely altered. Genes that do not react normally to their regulators' activity can provide explanations for the tumoral behavior, and be characteristic of cancer subtypes. We thus propose a statistical methodology to identify the misregulated g...

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Detalles Bibliográficos
Autores principales: Picchetti, Thomas, Chiquet, Julien, Elati, Mohamed, Neuvial, Pierre, Nicolle, Rémy, Birmelé, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674863/
https://www.ncbi.nlm.nih.gov/pubmed/26679516
http://dx.doi.org/10.1186/1752-0509-9-S6-S6