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Identifying representative drug resistant mutants of HIV

BACKGROUND: Drug resistance is one of the most important causes for failure of anti-AIDS treatment. During therapy, multiple mutations accumulate in the HIV genome, eventually rendering the drugs ineffective in blocking replication of the mutant virus. The huge number of possible mutants precludes e...

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Detalles Bibliográficos
Autores principales: Yu, Xiaxia, Weber, Irene T, Harrison, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674865/
https://www.ncbi.nlm.nih.gov/pubmed/26678327
http://dx.doi.org/10.1186/1471-2105-16-S17-S1