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CD49d is a disease progression biomarker and a potential target for immunotherapy in Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene. The immune inflammatory response also contributes to disease progression in DMD patients. In a previous study, we demonstrated higher levels of circulating CD49dhi and CD49ehi T cells in DMD patients compare...

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Detalles Bibliográficos
Autores principales: Pinto-Mariz, Fernanda, Rodrigues Carvalho, Luciana, Prufer De Queiroz Campos Araujo, Alexandra, De Mello, Wallace, Gonçalves Ribeiro, Márcia, Cunha, Maria Do Carmo Soares Alves, Cabello, Pedro Hernan, Riederer, Ingo, Negroni, Elisa, Desguerre, Isabelle, Veras, Mariana, Yada, Erica, Allenbach, Yves, Benveniste, Olivier, Voit, Thomas, Mouly, Vincent, Silva-Barbosa, Suse Dayse, Butler-Browne, Gillian, Savino, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674917/
https://www.ncbi.nlm.nih.gov/pubmed/26664665
http://dx.doi.org/10.1186/s13395-015-0066-2