Reduced numbers of switched memory B cells with high terminal differentiation potential in Down syndrome

Children with Down syndrome (DS) have increased susceptibility to infections and a high frequency of leukemia and autoimmune disorders, suggesting that immunodeficiency and immune dysfunction are integral parts of the syndrome. A reduction in B-cell numbers has been reported, associated with moderat...

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Detalles Bibliográficos
Autores principales: Carsetti, Rita, Valentini, Diletta, Marcellini, Valentina, Scarsella, Marco, Marasco, Emiliano, Giustini, Ferruccio, Bartuli, Andrea, Villani, Alberto, Ugazio, Alberto G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674966/
https://www.ncbi.nlm.nih.gov/pubmed/25472482
http://dx.doi.org/10.1002/eji.201445049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674966/
https://www.ncbi.nlm.nih.gov/pubmed/25472482
http://dx.doi.org/10.1002/eji.201445049

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