Role of ABCA7 loss-of-function variant in Alzheimer's disease: a replication study in European–Americans

INTRODUCTION: A recent study found a significant increase of ABCA7 loss-of-function variants in Alzheimer’s disease (AD) cases compared to controls. Some variants were located on noncoding regions, but it was demonstrated that they affect splicing. Here, we try to replicate the association between A...

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Detalles Bibliográficos
Autores principales: Del-Aguila, Jorge L., Fernández, Maria Victoria, Jimenez, Jessica, Black, Kathleen, Ma, Shengmei, Deming, Yuetiva, Carrell, David, Saef, Ben, Howells, Bill, Budde, John, Cruchaga, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675010/
https://www.ncbi.nlm.nih.gov/pubmed/26654793
http://dx.doi.org/10.1186/s13195-015-0154-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675010/
https://www.ncbi.nlm.nih.gov/pubmed/26654793
http://dx.doi.org/10.1186/s13195-015-0154-x

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