Incorporation of subject-level covariates in quantile normalization of miRNA data

BACKGROUND: Most currently-used normalization methods for miRNA array data are based on methods developed for mRNA arrays despite fundamental differences between the data characteristics. The application of conventional quantile normalization can mask important expression differences by ignoring dem...

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Detalles Bibliográficos
Autores principales: Suyundikov, Anvar, Stevens, John R., Corcoran, Christopher, Herrick, Jennifer, Wolff, Roger K., Slattery, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675058/
https://www.ncbi.nlm.nih.gov/pubmed/26653287
http://dx.doi.org/10.1186/s12864-015-2199-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675058/
https://www.ncbi.nlm.nih.gov/pubmed/26653287
http://dx.doi.org/10.1186/s12864-015-2199-4

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