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Antigen-dependent and –independent contributions to primary memory CD8 T cell activation and protection following infection
Memory CD8 T-cell activation, including expression of IFN-γ and granzymeB, can be induced by antigen (Ag)-dependent signals through the T-cell-receptor, or by pathogen-derived inflammatory cytokines in an Ag-independent manner. Recent studies have come to conflicting results regarding the contributi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675085/ https://www.ncbi.nlm.nih.gov/pubmed/26658291 http://dx.doi.org/10.1038/srep18022 |