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Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1

The spindle assembly checkpoint (SAC) monitors microtubule attachment to kinetochores to ensure accurate sister chromatid segregation during mitosis. The SAC members Bub1 and BubR1 are paralogs that underwent significant functional specializations during evolution. We report an in-depth characteriza...

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Detalles Bibliográficos
Autores principales: Breit, Claudia, Bange, Tanja, Petrovic, Arsen, Weir, John R., Müller, Franziska, Vogt, Doro, Musacchio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675524/
https://www.ncbi.nlm.nih.gov/pubmed/26658523
http://dx.doi.org/10.1371/journal.pone.0144673