Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers

OBJECTIVE: Phosphoinositide 3-kinase γ (PI3Kγ) is a G-protein-coupled receptor-activated lipid kinase mainly expressed in leukocytes and cells of the cardiovascular system. PI3Kγ plays an important signaling role in inflammatory processes. Since subclinical inflammation is a hallmark of atherosclero...

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Detalles Bibliográficos
Autores principales: Kächele, Martin, Hennige, Anita M., Machann, Jürgen, Hieronimus, Anja, Lamprinou, Apostolia, Machicao, Fausto, Schick, Fritz, Fritsche, Andreas, Stefan, Norbert, Nürnberg, Bernd, Häring, Hans-Ulrich, Staiger, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675530/
https://www.ncbi.nlm.nih.gov/pubmed/26658747
http://dx.doi.org/10.1371/journal.pone.0144494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675530/
https://www.ncbi.nlm.nih.gov/pubmed/26658747
http://dx.doi.org/10.1371/journal.pone.0144494

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