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Dengue Virus Directly Stimulates Polyclonal B Cell Activation

Dengue infection is associated to vigorous inflammatory response, to a high frequency of activated B cells, and to increased levels of circulating cross-reactive antibodies. We investigated whether direct infection of B cells would promote activation by culturing primary human B lymphocytes from hea...

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Detalles Bibliográficos
Autores principales: Correa, Arturo Ramon Vargas, Berbel, Ana Carolina Egypto Rosa, Papa, Michelle Premazzi, de Morais, Ana Theresa Silveira, Peçanha, Ligia Maria Torres, de Arruda, Luciana Barros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675537/
https://www.ncbi.nlm.nih.gov/pubmed/26656738
http://dx.doi.org/10.1371/journal.pone.0143391