Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis

Abundance of substrate receptor subunits of Cullin-RING ubiquitin ligases (CRLs) is tightly controlled to maintain the full repertoire of CRLs. Unbalanced levels can lead to sequestration of CRL core components by a few overabundant substrate receptors. Numerous diseases, including cancer, have been...

Descripción completa

Detalles Bibliográficos
Autores principales: Mathur, Radhika, Yen, James L., Kaiser, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675558/
https://www.ncbi.nlm.nih.gov/pubmed/26656496
http://dx.doi.org/10.1371/journal.pgen.1005727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675558/
https://www.ncbi.nlm.nih.gov/pubmed/26656496
http://dx.doi.org/10.1371/journal.pgen.1005727

Ejemplares similares