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Buprenorphine – an attractive opioid with underutilized potential in treatment of chronic pain
Despite proven clinical utility, buprenorphine has not been used widely for the treatment of chronic pain. Questions about “ceiling effect” or bell-shaped curve observed for analgesia in preclinical studies and potential withdrawal issues on combining with marketed μ-agonists continue to hinder prog...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675640/ https://www.ncbi.nlm.nih.gov/pubmed/26672499 http://dx.doi.org/10.2147/JPR.S85951 |