Development and validation of an immunohistochemistry assay to assess glucocorticoid receptor expression for clinical trials of mifepristone in breast cancer

BACKGROUND: Glucocorticoid receptor (GR) activity has been associated with chemotherapy resistance and poor outcomes in patients with triple negative breast cancer (TNBC). The aim of this study was to develop an immunohistochemistry (IHC) assay to assess GR expression in archival formalin-fixed, par...

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Detalles Bibliográficos
Autores principales: Baker, Gabrielle M, Murphy, Tiffany, Block, Thaddeus, Nguyen, Dat, Lynch, Frank J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675647/
https://www.ncbi.nlm.nih.gov/pubmed/26673410
http://dx.doi.org/10.2147/CMAR.S91546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675647/
https://www.ncbi.nlm.nih.gov/pubmed/26673410
http://dx.doi.org/10.2147/CMAR.S91546

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