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JEDI T-cells enable targeted cell depletion and investigation of T-cell interactions with virtually any cell population

There are numerous cell types with scarcely understood functions, and whose interactions with the immune system are not well characterized. To facilitate their study, we generated a mouse bearing enhanced green fluorescent protein (EGFP)-specific CD8+ T-cells. Transfer of the T-cells into EGFP repor...

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Detalles Bibliográficos
Autores principales: Agudo, Judith, Ruzo, Albert, Park, Eun Sook, Sweeney, Robert, Kana, Veronika, Wu, Meng, Zhao, Yong, Egli, Dieter, Merad, Miriam, Brown, Brian D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675673/
https://www.ncbi.nlm.nih.gov/pubmed/26524661
http://dx.doi.org/10.1038/nbt.3386