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Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury

Recent studies show the importance of mitochondrial dysfunction in the initiation and progression of acute kidney injury (AKI). However, no biomarkers exist linking renal injury to mitochondrial function and integrity. To this end, we evaluated urinary mitochondrial DNA (UmtDNA) as a biomarker of re...

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Detalles Bibliográficos
Autores principales: Whitaker, Ryan M., Stallons, L. Jay, Kneff, Joshua E., Alge, Joseph L., Harmon, Jennifer L., Rahn, Jennifer J., Arthur, John M., Beeson, Craig C., Chan, Sherine L., Schnellmann, Rick G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675682/
https://www.ncbi.nlm.nih.gov/pubmed/26287315
http://dx.doi.org/10.1038/ki.2015.240