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Improving a Synechocystis-based photoautotrophic chassis through systematic genome mapping and validation of neutral sites
The use of microorganisms as cell factories frequently requires extensive molecular manipulation. Therefore, the identification of genomic neutral sites for the stable integration of ectopic DNA is required to ensure a successful outcome. Here we describe the genome mapping and validation of five ne...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675711/ https://www.ncbi.nlm.nih.gov/pubmed/26490728 http://dx.doi.org/10.1093/dnares/dsv024 |