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A pivotal role for HOXB7 protein in endocrine resistant breast cancer

HOXB7 is a homeodomain containing transcription factor which plays a pivotal role in tamoxifen resistant breast cancer. Our work has shown that overexpression of HOXB7 renders cells tamoxifen resistant by mobilizing a number of receptor tyrosine kinase pathways. EGFR expression is upregulated by dir...

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Detalles Bibliográficos
Autores principales: Jin, Kideok, Sukumar, Saraswati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675788/
https://www.ncbi.nlm.nih.gov/pubmed/26697525