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Mechanism-based design of 2,3-benzodiazepine inhibitors for AMPA receptors
2,3-Benzodiazepine (2,3-BDZ) compounds represent a group of structurally diverse, small-molecule antagonists of (R, S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptors. Antagonists of AMPA receptors are drug candidates for potential treatment of a number of neurological dis...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675808/ https://www.ncbi.nlm.nih.gov/pubmed/26713266 http://dx.doi.org/10.1016/j.apsb.2015.07.007 |