Conformational Flip of Nonactivated HCN2 Channel Subunits Evoked by Cyclic Nucleotides

Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels are tetrameric proteins that evoke electrical rhythmicity in specialized neurons and cardiomyocytes. The channels are activated by hyperpolarizing voltage but are also receptors for the intracellular ligand adenosine-3′,5′-cyclic...

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Detalles Bibliográficos
Autores principales: Thon, Susanne, Schulz, Eckhard, Kusch, Jana, Benndorf, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Channels and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675818/
https://www.ncbi.nlm.nih.gov/pubmed/26636938
http://dx.doi.org/10.1016/j.bpj.2015.08.054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675818/
https://www.ncbi.nlm.nih.gov/pubmed/26636938
http://dx.doi.org/10.1016/j.bpj.2015.08.054

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