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Functional Heterogeneity in CD4(+) T Cell Responses Against a Bacterial Pathogen

To investigate how CD4(+) T cells function against a bacterial pathogen, we generated a Listeria monocytogenes-specific CD4(+) T cell model. In this system, two TCRtg mouse lines, LLO56 and LLO118, recognize the same immunodominant epitope (LLO(190-205)) of L. monocytogenes and have identical in vit...

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Detalles Bibliográficos
Autores principales: Milam, Ashley Viehmann, Allen, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675919/
https://www.ncbi.nlm.nih.gov/pubmed/26697015
http://dx.doi.org/10.3389/fimmu.2015.00621