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Functional Heterogeneity in CD4(+) T Cell Responses Against a Bacterial Pathogen
To investigate how CD4(+) T cells function against a bacterial pathogen, we generated a Listeria monocytogenes-specific CD4(+) T cell model. In this system, two TCRtg mouse lines, LLO56 and LLO118, recognize the same immunodominant epitope (LLO(190-205)) of L. monocytogenes and have identical in vit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675919/ https://www.ncbi.nlm.nih.gov/pubmed/26697015 http://dx.doi.org/10.3389/fimmu.2015.00621 |