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TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III

BACKGROUND: Transmembrane protein 106B (TMEM106B) has been identified as a risk factor for frontotemporal lobar degeneration, which is the second most common form of progressive dementia in people under 65 years of age. Mutations in charged multivesicular body protein 2B (CHMP2B), which is involved...

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Detalles Bibliográficos
Autores principales: Jun, Mi-Hee, Han, Jeong-Ho, Lee, Yu-Kyung, Jang, Deok-Jin, Kaang, Bong-Kiun, Lee, Jin-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676093/
https://www.ncbi.nlm.nih.gov/pubmed/26651479
http://dx.doi.org/10.1186/s13041-015-0177-z