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Lack of sex chromosome specific meiotic silencing in platypus reveals origin of MSCI in therian mammals

BACKGROUND: In therian mammals heteromorphic sex chromosomes are subject to meiotic sex chromosome inactivation (MSCI) during meiotic prophase I while the autosomes maintain transcriptional activity. The evolution of this sex chromosome silencing is thought to result in retroposition of genes requir...

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Detalles Bibliográficos
Autores principales: Daish, Tasman J., Casey, Aaron E., Grutzner, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676107/
https://www.ncbi.nlm.nih.gov/pubmed/26652719
http://dx.doi.org/10.1186/s12915-015-0215-4