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ESC reverses epithelial mesenchymal transition induced by transforming growth factor-β via inhibition of Smad signal pathway in HepG2 liver cancer cells

BACKGROUND: Epithelial mesenchymal transition (EMT) mediated by TGF-β pays an important role in malignant tumor acquired abilities of migration and invasion. Our previous study showed that the extract of Stellera chamaejasme L. (ESC) was against proliferation of a variety of tumor cells, but there w...

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Detalles Bibliográficos
Autores principales: Liu, Xiao-Ni, Wang, Shuang, Yang, Qing, Wang, Ya-Jie, Chen, De-Xi, Zhu, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676109/
https://www.ncbi.nlm.nih.gov/pubmed/26692820
http://dx.doi.org/10.1186/s12935-015-0265-2