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Discovery of Innovative Therapies for Rare Immune-Mediated Inflammatory Diseases via Off-Label Prescription of Biologics: The Case of IL-6 Receptor Blockade in Castleman’s Disease

Biologics have revolutionized the field of clinical immunology and proven to be both effective and safe in common immune-mediated inflammatory diseases (IMIDs) such as rheumatoid arthritis, inflammatory bowel diseases, and various hematological disorders. However, in patients with rare, severe IMIDs...

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Detalles Bibliográficos
Autores principales: Musters, Anne, Assaf, Amira, Gerlag, Danielle M., Tak, Paul P., Tas, Sander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4676110/
https://www.ncbi.nlm.nih.gov/pubmed/26697019
http://dx.doi.org/10.3389/fimmu.2015.00625